A visit to Mark Twain Region is a wonderful opportunity to explore the romantic lore of the mighty Mississippi River, which flows slowly and lazily along the eastern edge of the state.
Charming river towns and friendly villages welcome travelers to the Mark Twain Region, named for the beloved author who made this area his home.
No matter where you start or end your visit, you're sure to catch the spirit of the magnificent Mississippi River. The Mark Twain Region's unique blend of tradition, history, excitement and entertainment combine to create an experience you'll never forget.
Explore Mark Twain Region
The mighty Mississippi was the lifeblood of many Missouri towns for over a century. The Missouri Great River Road is a route with stories to tell and a history to preserve. Civil War History and the movement west are just two of the great American stories that the byway has to tell.Clarksville, MO Scenic Byways
With over 18,000 acres of water, Mark Twain Lake offers anglers thriving populations of catfish, bass, crappie, walleye, bluegill and sunfish. Timber has been left in the upper ends of the lake and in selected coves to improve fish habitat. According to 2004 reports: Bass. Based on 2003, MO Fishing
18,000 acres of sparkling waters and scenic lands of Clarence Cannon Dam and Mark Twain Lake make an ideal location for all types of water recreation. Boaters will find numerous boat ramps located conveniently around the lake as well as two full service marinas that offer boat and slip rentals., MO Boating
The Clarksville Tourist Information Center serves to showcase attractions and sights for those traveling the Great River Road. It overlooks the U. S. Lock and Dam #24, providing a close vantage point to view all river boat and barge traffic and a 'front row seat'Clarksville, MO Visitors Centers
A sculpture park featuring international and acclaimed American sculptors is located outside Louisiana. The project was started by Henry Lay, alumni of Saint Louis University, who wished to use his estate as a place to promote the arts in Northeast Missouri.Louisiana, MO Art