Clifford-Wirick House Antiques

River Heritage and Visitor Center

The Clarksville Tourist Information Center serves to showcase attractions and sights for those traveling the Great River Road. It overlooks the U. S. Lock and Dam #24, providing a close vantage point to view all river boat and barge traffic and a 'front row seat'

Clarksville Museum

The Clarksville Museum, operated by a volunteer board, covers the history of the town from its founding in 1817

The Great River Road Scenic Byway

The mighty Mississippi was the lifeblood of many Missouri towns for over a century. The Missouri Great River Road is a route with stories to tell and a history to preserve. Civil War History and the movement west are just two of the great American stories that the byway has to tell.

Crown Valley Port House

Historic Downtown District

The commercial district in Clarksville is listed on the National Register of Historic Places